Effect of Newborn Screening for Congenital Adrenal Hyperplasia

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Effect of newborn screening for congenital adrenal hyperplasia.

OBJECTIVE To compare the incidence of diagnosis and morbidity in newborns who were screened with newborns who were not screened for congenital adrenal hyperplasia (CAH). DESIGN A retrospective cohort study. SETTING Arkansas, Oklahoma, and Texas. PATIENTS An unscreened population in Arkansas and Oklahoma (n = 400118) was compared with a screened population in Texas (n = 1613378) during a 5...

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Newborn screening for congenital adrenal hyperplasia in New York State

From 2007 to 2014 the New York State (NYS) Newborn Screening (NBS) program screened 2 million newborns for congenital adrenal hyperplasia (CAH). The data was analyzed to determine factors that affect 17α-hydroxyprogesterone levels and assist in developing algorithm changes that would improve the positive predictive value of the methodology being used. The concentration of 17-OHP in dried blood ...

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Neonatal screening for congenital adrenal hyperplasia

459 Summary Objective: The effectiveness of neonatal screening for reducing morbimortality in children with congenital adrenal hyperplasia (CAH) is the main justification for its implementation. One of the challenges for its implementation is to determine the cutoff value for laboratory measurement of 17-hydroxyprogesterone (17OHP) with appropriate cost-effectiveness. This study identified fact...

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Newborn Screening for Congenital Adrenal Hyperplasia in India: What Do We Need to Watch Out for?

BACKGROUND Congenital Adrenal Hyperplasia (CAH) is a disorder-an ideal candidate to deserve newborn screening. CAH accounts for a significant mortality and morbidity in India, and its awareness among obstetricians should be treated as highly important to prevent the problem. PURPOSE OF THE STUDY It is very important for a country like India as the incidence of CAH is reasonably high justifyin...

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The case for newborn screening for congenital adrenal hyperplasia in Australia.

TO THE EDITOR: We write to encourage policy debate over newborn screening for congenital adrenal hyperplasia (CAH). Classical CAH is a severe, life-threatening disease affecting about one in 15 000 liveborn infants in Australia.1 An inexpensive screening test for newborns is available, but this test is not included in the current newborn screening program in Australia. Three-quarters of childre...

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ژورنال

عنوان ژورنال: Archives of Pediatrics & Adolescent Medicine

سال: 1999

ISSN: 1072-4710

DOI: 10.1001/archpedi.153.12.1272